Endocrine Abstracts

Aims: Previous reports have demonstrated that the adipocyte-derived peptide adiponectin is closely associated with insulin resistance due to its insulin-sensitizing and anti-inflammatory properties in peripheral tissues; however the autocrine effects of adiponectin remain elusive. This study investigated regulatory effects of adiponectin on glucose transport and insulin signalling in insulin-sensitive or insulin-resistant 3T3-L1 adipocytes.Methods: 3T3-L...

Background: There is no existing longitudinal study to support ethnicity-specific and body mass index (BMI) category-specific waist circumference (WC) thresholds and their potential clinical utility to assess the risk of obesity-related diseases.Methods: We performed a prospective assessment of 5,852,702 subjects in large-scale population-based cohort dataset obtained from the Korea National Health Insurance System. BMI was categorized into 6 subgroups (...